Mutagenic Effect of Streptomyces Avermitilis Progressivity Irradiated by Ion Beam of 12C6+
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Graphical Abstract
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Abstract
Mutagenic effect on the mutant highproducing strain ZJAVY1203 and the original strain ZJAVA1 irradiated by ion beam of 12C6+ have been investigated. The experimental results indicated that the original strain has higher survival rate and stronger resistance to radiation than mutant highproducing Strain at dose of 10 Gy. The mutant highproducing strain has higher survival rate and stronger resistance to radiation than the original strain at the dose higher than 30 Gy. The lethality was 97% and the highest rate of orthomutation was 34.2%, when ZJAV A1 was irradiated by 50 Gy 12C6+ beam. The lethality was 94.97% and the highest rate of orthomutation was 23.5% when ZJAVY1203 was irradiated by 30 Gy 12C6+ beam. The best radiation dose is decreased by progressivity irradiation.
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