Progress on Finding Novel MicroRNAs and Expectation of Heavy Ion Irradiation Application in This Field
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Graphical Abstract
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Abstract
MicroRNAs(miRNAs) are one kind of small noncoding RNAs of 19—24 nucleotides that transcriptionally regulate the expression of target genes by binding to their mRNA and thus play a central role in gene regulation in a wide arrange of biological processes. In this paper, we reviewed the clone and identification of novel miRNAs, summarized recent work on novel human miRNA recognization, and proposed a potentially feasible way to discover more human miRNAs.
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