Biological Effect Induced by Radioactive Ion Beam and Corresponding Biophysical Mechanisms
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Graphical Abstract
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Abstract
The depthsurvival effect of a βdelayed particle decay 9C beam on human salivary gland (HSG) cells is presented in this paper. Compared with a stable 12Cion beam, the radioactive 9Cion beam showed an enhanced biological effect, i.e., remarkably enhanced efficiency in cell killing, at the penetration depths around its Bragg peak. The biophysical mechanisms underlying the enhanced biological effect are discussed herein, and the latest progress in biological effect induced by another radioactive 8Bion beam is introduced. In the end of this paper, several topics concerning the frontier of the radiationinduced biological effects using radioactive ion beams are proposed.
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