Abstract: A vacuum control system was designed for the High Energy Photon Source(HEPS) booster and transport line, which features a large number of devices, wide distribution, and complex vacuum valve control logic. The system utilizes Yokogawa PLC for valve control and interlock logic, converting PLC variables into EPICS PVs. Vacuum data is retrieved by the IOC running on embedded industrial control computers via the TCP/IP protocol. Touch screens are employed for local valve control, and the GUI is developed with iX Developer. The operator interface developed using Control System Studio enables remote monitoring of the vacuum system. The system's modular design for both software and hardware enhances flexibility, reusability, and maintainability. Touch screens at any station enable centralized control of all valve operations, effectively overcoming the challenges posed by the widespread distribution of equipment. Since its installation and commissioning in May 2023, the vacuum control system has operated reliably with an interlock response time of approximately 18 ms, meeting all design requirements.